摘要：The long-term objective of this three-year project, which began in 2023, is to formulate guidance and other sources of information for developers, healthcare professionals, patients and the public to clarify the regulatory and evaluation requirements for DMHTs. In this way, DMHTs will be assessed in a risk-proportionate and consistent manner, enabling access to safe and effective products to improve outcomes for people with mental health conditions. The first work package of the project has now ...

摘要：The event began with an address from Major General Duncan G Forbes, the Royal Navy’s Director of Strategy and Policy, and Assistant Chief of the Naval Staff. He gave a shout out to his old captain and mentor Brigadier Jock Fraser, who retires this summer, before fittingly highlighting his lecture’s theme of legacy. The Major General discussed the broad strategic context of the Navy’s current work, while promising to use the occasion to tell stories, kindle relationships and rest. He then proceed...

摘要：The Department for Levelling Up, Housing and Communities is pleased to confirm the reappointment of two current Non- Executive Directors (NEDs) for a further three years. Lord (Gary) Porter CBE and Jeffrey Dodds will continue to advise the department until June 2027. Lord Porter and Jeff Dodds joined the Board in 2021 and provide independent advice and challenge across multiple policies. Lord Porter offers a particular depth of experience from his career in local government and construction to a...

摘要：Rian O’Keeffe successfully applied for a ?50,000 Bounce Back Loan in July 2020 on behalf of what he claimed was his Trainersource business However, the business did not, and never had, existed O’Keeffe used the funds for general living expenses and had no intention of ever paying the loan back A fraudster who illegally secured a ?50,000 Bounce Back Loan designed to support businesses during the Covid pandemic has been handed a suspended sentence. Rian O’Keeffe, 28, was sentenced to 18 months in ...

摘要：Fact of the Week: US Export Controls Reduce Foreign Direct Investment in the US by 13 Percent. By? Ian Tufts May 6, 2024 Source: Naoto Jinji and Shunya Ozawa, “Impact of Technological Decoupling between the United States and China on Trade and Welfare,” Discussion papers, Research Institute of Economy, Trade and Industry (RIETI),no. 24-E-041 (March 2024). Commentary: A recent working paper by Naoto Jinji and Shunya Ozawa analyzed how the decoupling of the United States...

摘要：5月2日,中国科学院深圳先进技术研究院李洋团队在 Chemical Engineering Journal 在线发表了一篇题为 “Nano-assemblies overcome cancer multidrug resistance for effectively synergistic chemo-immuno-oncotherapy” 的研究文章。这项工作创新性的设计开发了两种基于DSPE-PEG的脂质聚合物DSPE-PEG-DOX和DSPE-PEG-PDA,分别用于在肿瘤微环境中低酸响应释放化疗药物-多柔比星 (DOX) 和缺氧响应释放聚多巴胺 (PDA) 。同时,在两种聚合物自组装过程中,芯层负载的佐剂-辛伐他汀 (SIM) 通过缓释到肿瘤微环境进一步增强免疫细胞浸润与活化。在多种化疗耐药动物肿瘤模型中,纳米组装体均表现出显著的抑制肿瘤生长,增强相关免疫细胞活化的作用。

摘要：Shaping a science system to support our national ambitions May 06, 2024 The Australian Academy of Science is developing a ten-year plan to demonstrate how science needs to evolve to achieve our national ambitions and advance Australian interests locally and globally. ‘Australian Science, Australia’s Future: Science 2035’ will assess the capability of Australia’s science system, its ability to compete and collaborate globally, and its contribution to the nation’s economy, security, health?and qua...

摘要：6 May Oxford Instruments awarded King’s Award for Enterprise in Innovation Oxford Instruments, a market-leading technology company with a track record of over 60 years of accelerating scientific breakthroughs, has been awarded the King's Award for Enterprise in Innovation for its Symmetry detector. Symmetry was created to enable deeper understanding of a wide range of materials, analysing their properties with incredible precision. With its ability to operate at the nanoscale – that is, to billi...

摘要：Timpson Group, who have received the award for Promoting Opportunity through social mobility for their work providing training and employment opportunities to marginalised groups Halo Solutions Ltd, producers of lifesaving crowd safety and security software invented by former national counter-terrorism police officer Lloyd Major, who wanted to improve emergency communications, safety and security in venues and public spaces after the Manchester Arena bombing. Halo Solutions have been recognised ...

摘要：Key Takeaways Contents Key Takeaways 1 Introduction . 2 Background: Need for New Evidence Relating Expected Financial Return for Drugs to?R&D . 3 Addressing Gaps in the Evidence to Inform Drug Policy Decisions 4 Improvements In Decision Simulation Model: Represent Effect on Capital Allocation for?R&D . 5 Call to Action: Improving the Assessment of Policy Impacts on Drug?Development 6 Endnotes 8 Introduction A significant body of evidence suggests there is a positive relationship between the expe...